HLAB27 REAL-TIME PCR e тест за бърза групово-специфична детекция за HLA-B27 (Главен комплекс на тъканна съвместимост,клас I, B). Човешкият левкоцитен антиген В27 (HLA-B27) е протеин, разположен на повърхността
PCRbased methods are widely used for HLA-B*27 screening. To refine HLA-B*27 testing we aimed at establishing a real-time PCR protocol to detect the HLA-B*27 allele directly
Metoda Průtoková cytometrie Stanovení exprese antigenu HLA-B27 monoklonálními protilátkami. Měření se provádí na průtokovém cytometru. V případě pozitivity se provádí test s antigenem HLA-B7 (nejčastější výskyt zkřížené reaktivity). Typ materiálu. Venózní krev s K2EDTA, K3EDTA (VACUTAINER - fialový uzávěr) nebo
ClinicalSignificance. HLA-B27 Antigen - HLA-B27 is found in 90% of patients with ankylosing spondylitis and 80% in Reiter's disease. Ankylosing spondylitis affects 1 in 1000 caucasians. Ankylosing spondylitis is 10 times more common among individuals with HLA-B27 compared to individuals without this antigen.
HLAB27 este extrem de heterogen descriindu-se peste 35 subtipuri moleculare (HLA-B*2701 – B*2736). Subtipurile HLA-B27 difera prin anumiti aminoacizi care foarte probabil sunt implicati in legarea peptidelor antigenice specifice. Subtipurile asociate in mod cert cu spondilita ankilopoietica, sunt HLA-B*2705, HLA-B*2702, HLA-B*2704, HLA-B
APCR detection method for HLA-class I and II genes has been used by us for tissue typing of transplant patients, and was used as a starting point in the present study.
Material Sangue total com EDTA. Sinônimo: Pesquisa do HLA B27 histocompatibilidade. Método: PCR (Reação em Cadeia p/ Polimerase) - Sistema Sybr Green. Interpretação: A
Thisreal-time PCR test kit is for the detection of Human leukocyte antigen B27 in whole blood. HLA-B27 is strongly associated with ankylosing spondylitis (AS) and other related inflammatory diseases, such as
HLA27- HLA B27 - DETECÇÃO POR PCR. SINÔNIMOS: ANTÍGENO LEUCOCITÁRIO HUMANO (HLA) B27, HLA-B27, HLAB27, Espondilite, doenças reumáticas,
TheHLA-B27 is a blood test that is used to determine the level of a particular protein called human leukocyte antigen B27 (HLA-B27), which is also a genetic marker. The protein is an antigen that is found on the surface of white blood cells that are fighting infection in the body. Its basic purpose is to help the immune system in
HLAB27 is strongly associated with ankylosing spondylitis (AS). HLA-B27 is also associated with other seronegative arthropathies such Reiter syndrome and psoriatic
Thepresence of the HLA-B27 antigen is strongly associated with AS and a few other rheumatic disorders (Reiter’s syndrome, acute anterior uveitis, and inflammatory bowel disease [3,4]. HLA-B27 testing is routinely used to diagnose AS since the HLA-B27 surface antigen is expressed in 90% of AS patients as compared to 8% of healthy
Thecorrelation between the presence of HLA-B27 and ankylosing spondylitis has been a known entity since the early 1970s. Although common in the general population, this allele strongly contributes to the susceptibility of development of the linked family of inflammatory rheumatologic conditions collectively known as spondyloarthritis. Additional
ProductDescription. The HISTO TYPE B*27 quantitative real-time PCR kit is used for the molecular genetic detection of HLA-B*27 alleles. The HLA-B*27 protein is a variant of the human leucocyte antigen-B (HLA-B) and is associated with different autoimmune diseases (Morbus Bechterew or Ankylosing Spondylitis, Reiter’s disease, reactive arthritis) and is,
Genotypingof HLA-B27 by real-time PCR without hybridization probes. This molecular biological assay, based on allele-specific PCR, unambiguously identified all B27 -positive samples except for the rare B2707 subtype and provides a convenient, rapid way to detect and quantify any PCR product, regardless of sequence.
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hla b27 detecção por pcr
